Under 
Construction| Target | Toxin | PubMed | Comments | Species |
|---|
| Acid sensitive ion channels | PcTx2 | PubMed | Inhibits ASIC1a | Psalmopoeus cambridgei |
| Calcium channels | Argiotoxins | PubMed | These include a variety of polyamine toxins found in the genus Argiope. | Argiope |
| Calcium channels | PLTX II | PubMed | Plectreurys toxin II has an unusually greasy or amphipathic peptide with O-palmitoylated serine. It blocks presynaptic calcium channels in insects. | Plectreurys tristis |
| Capsaicin receptors | AG505 | PubMed | AG489 and AG505 are acylpolyamine toxins from Agelenopsis aperta, which block capsaicin (TRPV1) channels. | Agelenopsis aperta |
| Capsaicin receptors | AG489 | PubMed | AG489 and AG505 are acylpolyamine toxins from Agelenopsis aperta, which block capsaicin (TRPV1) channels. |
|
| Capsaicin receptors | Vanillotoxin 1 | PubMed | Vanillotoxins 1, 2 and 3 are peptide activators of capsaicin activated (TRPV1) ion channels. | Psalmopoeus cambridgei |
| Capsaicin receptors | Vanillotoxin III | PubMed | Vanillotoxins 1, 2 and 3 are peptide activators of capsaicin activated (TRPV1) ion channels. | Psalmopoeus cambridgei |
| Capsaicin receptors | Vanillotoxin 2 | PubMed | Vanillotoxins 1, 2 and 3 are peptide activators of capsaicin activated (TRPV1) ion channels. | Psalmopoeus cambridgei |
| Glutamate receptors | JSTX | PubMed | Joro spider toxin was the first of many polyamine toxins to be characterized from spiders. It blocks glutamate receptors. | Nephila clavata |
| Neurotransmitter release | Alpha Latrotoxin | PubMed |
| Latrodectus tredecimguttatus |
| Potassium channels | Hanatoxin | PubMed |
| Grammostola rosea |
| Potassium channels | GxTX-1 | PubMed | Inibits mammalian Kv2.1/Kv2.2 potassium channels. This toxin has been used to demonstrate a new way to enhance glucose dependent secretion in type II diabetes. | Plesiophrictus guangxiensis |
| Potassium channels | Vanillotoxin 1 | PubMed | Vanillotoxins 1, 2 and 3 are peptide activators of capsaicin activated (TRPV1) ion channels. | Psalmopoeus cambridgei |
| Potassium channels | Vanillotoxin III | PubMed | Vanillotoxins 1, 2 and 3 are peptide activators of capsaicin activated (TRPV1) ion channels. | Psalmopoeus cambridgei |
| Sodium Channels | JZTX-I | PubMed | Jingzhaotoxin-I is reported to increase the strength and rate of vertebrate heart beats, possibly via inhibition of cardiac sodium channels. | Chilobrachys jing-zhao |
| Sodium Channels | DTX9.2 | PubMed | Causes spike discharges and depolarization of insect neurons. | Diguetia canities |
| Sodium Channels | Hainantoxin III | PubMed | Blocks tetrotoxin insensitive sodium channels | Selenocosmia hainana |
| Sodium Channels | Hainantoxin I | PubMed | Blocks insect sodium channels | Selenocosmia hainana (=Ornithoctonus hainana) |
| Sodium Channels | Hainantoxin V | PubMed | Inhibits tetrodotoxin sensitive ion channels | Selenocosmia hainana |
| Sodium Channels | ProTx-II | PubMed | ProTx-I and ProTx-II inhibit activation of tetrodotoxin resistant peripheral nerve voltage activated sodium channels, with some activity against tetrodotoxin sensitive sodium channels. | Thrixopelma pruriens |
| Sodium Channels | ProTx-I | PubMed | ProTx-I and ProTx-II inhibit activation of tetrodotoxin resistant peripheral nerve voltage activated sodium channels, with some activity against tetrodotoxin sensitive sodium channels. | Thrixopelma pruriens |
| Stretch activated ion channels | GsMtx4 | PubMed | Blocks stretch activated ion channels. | Grammostola rosae (brown morph) |
